ツール：生体シミュレーション

資料：生体シミュレーションツール

PhysioDesigner

CellML Project

OpenCOR

Chaste

CARPentry

  • https://carp.medunigraz.at/carputils/install/index.html
  • 心臓形状モデルに線維走行を埋め込むツールなど
  • J. D. Bayer et al., A Novel Rule-Based Algorithm for Assigning Myocardial Fiber Orientation to Computational Heart Models. Ann Biomed Eng. 2012 October ; 40(10): 2243–2254. doi:10.1007/s10439-012-0593-5.

Myokit

  • http://myokit.org/
  • Myokit is a python-based software package designed to simplify the use of numerical models in the analysis of cardiac myocytes.
  • M. Clerx et al., Myokit: A simple interface to cardiac cellular electrophysiology. Progress in Biophysics and Molecular Biology 120 (2016) 100e114 http://dx.doi.org/10.1016/j.pbiomolbio.2015.12.008
  • この論文は Myokit の紹介だが，2016年時点での関連ツールが網羅的にまとめられている．

Maastricht antiarrhythmic drug evaluator (MANTA)

  • Myokitの拡張
  • A computational tool for better understanding of antiarrhythmic drugs だそうで
  • Python
  • H. Sutano et al., Maastricht antiarrhythmic drug evaluator (MANTA): A computational tool for better understanding of antiarrhythmic drugs, Pharmacological Research, Volume 148, October 2019, 104444. doi:10.1016/j.phrs.2019.104444

Cardiac mechanics

Multiscale Cardiac Simulation Framework (MSCSF)

MedalCare-XL

資料：生体シミュレーションツール